Article
DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children.
Human molecular genetics - 1 May 1999
Fisher P J, Turic D, Williams N M, McGuffin P, Asherson P, Ball D, Craig I, Eley T, Hill L, Chorney K, Chorney M J, Benbow C P, Lubinski D, Plomin R, Owen M J
Abstract excerpt
General cognitive ability (g), which is related to many aspects of brain functioning, is one of the most heritable traits in neuroscience. Similarly to other heritable quantitatively distributed traits, genetic influence on g is likely to be due to the combined action of many genes of small effect [quantitative trait loci (QTLs)], perhaps several on each chromosome. We used DNA pooling for the first time to...
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