Phenotype-determining genes in inflammatory bowel disease.

Abstract excerpt

Inflammatory bowel disease (IBD) has traditionally been categorized as either ulcerative colitis or Crohn's disease on the basis of clinical, radiological and histological criteria. Within these diseases however, significant heterogeneity is observed, suggesting the existence of phenotypic subtypes, based on features such as location and behaviour of disease. Evidence for a possible genetic basis for these...

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