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Article

PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus.

The Journal of clinical investigation - 1 Apr 1999

Tsao B P, Cantor R M, Grossman J M, Shen N, Teophilov N T, Wallace D J, Arnett F C, Hartung K, Goldstein R, Kalunian K C, Hahn B H, Rotter J I

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by various autoantibodies that recognize autoantigens displayed on the surface of cells undergoing apoptosis. The genetic contribution to SLE susceptibility has been widely recognized. We previously reported evidence for linkage to SLE of the human chromosome 1q41-q42 region and have now narrowed it from 15 to 5 cM in an extended sample...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Linkage Disequilibrium

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Source

Open in PubMed Open full text

Identifiers

PMID: 10207165
DOI: 10.1172/JCI5967
PMCID: PMC408279

Genes

TGFB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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