Article
Genetic gains and losses in oral squamous cell carcinoma: impact on clinical management.
Cellular oncology (Dordrecht, Netherlands) - 1 Feb 2014
Ribeiro Ilda Patrícia, Marques Francisco, Caramelo Francisco, Pereira João, Patrício Miguel, Prazeres Hugo, Ferrão José, Julião Maria José, Castelo-Branco Miguel, de Melo Joana Barbosa, Baptista Isabel Poiares, Carreira Isabel Marques
Abstract excerpt
PURPOSE: The identification of genetic markers associated with oral cancer is considered essential to improve the diagnosis, prognosis, early tumor and relapse detection and, ultimately, to delineate individualized therapeutic approaches. Here, we aimed at identifying such markers. METHODS: Multiplex Ligation-dependent Probe Amplification (MLPA) analyses encompassing 133 cancer-related genes were performed on a...
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