Article
Hemoglobin S/O(Arab): thirteen new cases and review of the literature.
American journal of hematology - 1 Apr 1999
Zimmerman S A, O'Branski E E, Rosse W F, Ware R E
Abstract excerpt
Hemoglobin S/O(Arab) (Hb S/O(Arab)) is a rare compound heterozygous hemoglobinopathy characterized by the presence of two variant beta-globin chains: beta6Glu --> Val (Hb S) and beta121Glu --> Lys (Hb O(Arab)). The diagnosis of Hb S/O(Arab) requires electrophoresis on both cellulose acetate and citrate agar, since Hb O(Arab) co-migrates with Hb C at alkaline pH and close to Hb S at acidic pH. To date only case...
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