Article
Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign.
British journal of haematology - 1 Feb 2014
Alsultan Abdulrahman, Alabdulaali Mohammed K, Griffin Paula J, Alsuliman Ahmed M, Ghabbour Hazem A, Sebastiani Paola, Albuali Waleed H, Al-Ali Amein K, Chui David H K, Steinberg Martin H
Abstract excerpt
Sickle cell disease (SCD) in Saudi patients from the Eastern Province is associated with the Arab-Indian (AI) HBB (β-globin gene) haplotype. The phenotype of AI SCD in children was described as benign and was attributed to their high fetal haemoglobin (HbF). We conducted a hospital-based study to assess the pattern of SCD complications in adults. A total of 104 patients with average age of 27 years were enrolled....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.