Article
Diagnosis and characterization of Hb C/Hb Iowa: a rare but easily misidentified compound heterozygous condition.
Hemoglobin - 1 Feb 2004
Somjee Saika, Yu Lolie C, Hagar Arthur F, Hempe James M
Abstract excerpt
Hb Iowa is a rare hemoglobin (Hb) variant with a Gly --> Ala substitution at position 119 of beta-globin. It was previously reported only in an African American infant who was also heterozygous for Hb S [beta6(A3)Glu --> Val] and her mother (Hb A/Iowa). Here we describe the second report of Hb Iowa, the first in conjunction with Hb C [beta6(A3)Glu --> Lys]. The patient was an African American girl, originally...
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