Article
Dexamethasone induces apoptosis in human T cell clones expressing low levels of Bcl-2.
Cell death and differentiation - 1 Jan 1999
Gilardini Montani M S, Tuosto L, Giliberti R, Stefanini L, Cundari E, Piccolella E
Abstract excerpt
Previous results of ours have demonstrated that the same clonotype can express both a sensitive and a resistant phenotype to Dex-mediated PCD induction depending on its cell cycle phase. In particular, we demonstrated that human T lymphocytes, arrested in the G0/G1 phase of the cell cycle, are susceptible, while proliferating T cells are resistant to Dex-mediated apoptosis. In this paper, we have further...
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