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Article

Kinetic model for integrin-mediated adhesion release during cell migration.

Annals of biomedical engineering - 1 Jan 2000

Palecek S P, Horwitz A F, Lauffenburger D A

Abstract excerpt

Under many circumstances, cell migration speed is limited by the rate of cell-substratum detachment at the cell rear. We have constructed a mathematical model to integrate how the biophysical and biochemical interactions between integrins, the cytoskeleton, and the matrix affect rear retraction a...

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Identifiers

PMID: 10199699
DOI: 10.1114/1.176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10199699-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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