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Article

The influence of cell phenotype on collective cell invasion into the extracellular matrix.

Bulletin of mathematical biology - 26 Dec 2025

Yin Yuan, Waters Sarah L, Baker Ruth E

Abstract excerpt

Understanding the interactions between cells and the extracellular matrix (ECM) during collective cell invasion is crucial for advancements in tissue engineering, cancer therapies, and regenerative medicine. This study focuses on the roles of contact guidance and ECM remodelling in directing cell behaviour, with a particular emphasis on exploring how differences in cell phenotype impact collective cell invasion....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41452381
DOI: 10.1007/s11538-025-01560-9
PMCID: PMC12743096

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