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Article

Enrichment of a precore-minus mutant of duck hepatitis B virus in experimental mixed infections.

Journal of virology - 1 May 1999

Zhang Y Y, Summers J

Abstract excerpt

A precore-deficient mutant of duck hepatitis B virus (DHBV) produced by site-directed mutagenesis was tested for its ability to compete with wild-type virus in a mixed infection of 3-day-old ducklings. The mutation was shown to produce a cis-acting defect, resulting in a replication rate that was about one-half that of wild-type virus. Accordingly, wild-type virus was rapidly selected during the spread of...

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Identifiers

PMID: 10196253
DOI: 10.1128/JVI.73.5.3616-3622.1999
PMCID: PMC104136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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