Article
Competition in vivo between a cytopathic variant and a wild-type duck hepatitis B virus.
Virology - 10 Nov 1998
Lenhoff R J, Luscombe C A, Summers J
Abstract excerpt
Several examples of human hepatitis B virus strains with enhanced replication in vitro have been described. To understand whether this characteristic could be a cause of liver disease, we have studied a variant of the closely related duck hepatitis B virus (DHBV) that had enhanced levels of cccDN...
Topics
- Animals
- Cells, Cultured
- Chickens
- Cytopathogenic Effect, Viral
- DNA, Viral
- Ducks
- Genotype
- Hepadnaviridae Infections
- Hepatitis B Virus, Duck
- Immunohistochemistry
- Liver
- Liver Neoplasms
- Mutation
- Polymerase Chain Reaction
- Transfection
- Tumor Cells, Cultured
- Viremia
- Virus Replication
