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Photoperiodic Control of the Rat Pineal Arylalkylamine-N-Acetyltransferase and Hydroxyindole-O-Methyltransferase Gene Expression and Its Effect on Melatonin Synthesis

1 Apr 1999

Abstract excerpt

Photoperiodic changes of pineal melatonin (MEL) profile are accompanied by parallel changes of arylalkylamine-N-acetyltransferase (AA-NAT) activity. In the present study, the authors investigated, for the first time, whether two other important variables of pineal metabolism, AA-NAT and hydroxyindole-O-methyltransferase (HIOMT) gene expression, also may be affected by the photoperiod. Evening rises in AA-NAT and...

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PMID: 10194646
DOI: 10.1177/074873099129000489

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