Article
Activated CD8+ T cells in secondary progressive MS secrete lymphotoxin.
Neurology - 25 Feb 2003
Buckle Guy J, Höllsberg Per, Hafler David A
Abstract excerpt
The authors compared the functional activation state and cytokine secretion profile of CD8+ T cells in patients with relapsing-remitting and secondary progressive (SP) MS to those in normal controls. In addition, they examined cytokine secretion in relationship to single nucleotide polymorphism (SNP) analysis of cytokine genes. A significant increase in lymphotoxin secretion from anti-CD3-stimulated CD8+ T cells...
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