Article
GGF/neuregulin induces a phenotypic reversion of oligodendrocytes.
Molecular and cellular neurosciences - 1 Feb 1999
Canoll P D, Kraemer R, Teng K K, Marchionni M A, Salzer J L
Abstract excerpt
We have previously shown that glial growth factor (GGF), a member of the neuregulin (NRG) family of growth factors, is a mitogen and survival factor for oligodendrocyte progenitors in cell culture and blocks their differentiation at the pro-oligodendrocyte stage (P. D. Canoll et al., 1996, Neuron 17, 229-243). We now show that GGF is able to induce differentiated oligodendrocytes to undergo a phenotypic reversion...
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