Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture.

doi:10.3390/cells13080668

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Article

Reversal of Postnatal Brain Astrocytes and Ependymal Cells towards a Progenitor Phenotype in Culture.

Cells - 12 Apr 2024

Kakogiannis Dimitrios, Kourla Michaela, Dimitrakopoulos Dimitrios, Kazanis Ilias

Abstract excerpt

Astrocytes and ependymal cells have been reported to be able to switch from a mature cell identity towards that of a neural stem/progenitor cell. Astrocytes are widely scattered in the brain where they exert multiple functions and are routinely targeted for in vitro and in vivo reprogramming. Ependymal cells serve more specialized functions, lining the ventricles and the central canal, and are multiciliated,...

Topics

Animals
Astrocytes
Ependyma
Phenotype
Mice
Cells, Cultured
Neural Stem Cells
Cell Differentiation
Brain
Rats
SOXB1 Transcription Factors
Mice, Inbred C57BL
Mitosis
Glycogen Synthase Kinase 3
Animals, Newborn

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Identifiers

PMID: 38667283
DOI: 10.3390/cells13080668
PMCID: PMC11049274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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