Article
Genetic and physical mapping of the CLN6 gene on chromosome 15q21-23.
Molecular genetics and metabolism - 1 Apr 1999
Sharp J D, Wheeler R B, Lake B D, Fox M, Gardiner R M, Williams R E
Abstract excerpt
CLN6, the gene for a variant late infantile neuronal ceroid lipofuscinosis, has been mapped to chromosome 15q21-23 by homozygosity mapping. At present the family resource consists of 31 families. By the analysis of additional polymorphic markers in this resource the critical region has been narrowed down from 12 cM to less than 4 cM. A physical map is being constructed using YAC and PAC clones as a prerequisite...
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