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Article

Chromosomal localization of two genes underlying late-infantile neuronal ceroid lipofuscinosis.

Neurogenetics - 1 Mar 1998

Haines J L, Boustany R M, Alroy J, Auger K J, Shook K S, Terwedow H, Lerner T J

Abstract excerpt

Classical late-infantile neuronal ceroid lipofuscinosis (LINCL; CLN2) is an inherited neurodegenerative disorder of childhood characterized by seizures, loss of vision, and progressive motor and mental deterioration. The hallmark of this disease is the accumulation of enlarged, secondary lysosomes packed with curvilinear bodies in cells of affected individuals. The biochemical basis of LINCL remains unknown and...

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Source

Identifiers

PMID: 10737126
DOI: 10.1007/s100480050032

Genes

CLN6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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