Article
Ovine neuronal ceroid lipofuscinosis: a large animal model syntenic with the human neuronal ceroid lipofuscinosis variant CLN6.
Journal of medical genetics - 1 Sept 1998
Broom M F, Zhou C, Broom J E, Barwell K J, Jolly R D, Hill D F
Abstract excerpt
The neuronal ceroid lipofuscinoses (NCLs) are a group of inherited degenerative neurological diseases affecting children. A number of non-allelic variants have been identified within the human population and the genes for some of these have recently been identified. The underlying mechanism for t...
Topics
- Age of Onset
- Animals
- Chromosome Mapping
- Chromosome Painting
- Chromosomes, Human, Pair 15
- Disease Models, Animal
- Female
- Genetic Variation
- Humans
- Male
- Neuronal Ceroid-Lipofuscinoses
- Pedigree
- Sheep