Article
Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. The EARS Group.
European journal of clinical investigation - 1 Feb 1999
Gudnason V, Kakko S, Nicaud V, Savolainen M J, Kesäniemi Y A, Tahvanainen E, Humphries S
Abstract excerpt
BACKGROUND: Variation at the cholesteryl ester transfer protein (CETP) gene locus has been implicated in determining the levels and activity of CETP, apoAI and high-density lipoprotein (HDL) plasma concentration and the risk of developing coronary artery disease. STUDY DESIGN: The effects of two common polymorphisms of CETP, TaqIB in intron 1 and isoleucine 405 to valine (I405-->V) in exon 14, were examined in a...
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