Article
Concerted expression of BK virus large T- and small t-antigens strongly enhances oestrogen receptor-mediated transcription.
The Journal of general virology - 1 Mar 1999
Moens U, Van Ghelue M, Johansen B, Seternes O M
Abstract excerpt
Previous studies have shown that the human polyomavirus BK (BKV) genome contains an oestrogen response element (ERE). This isolated element binds its cognate receptor in vitro and can mediate 17beta-oestradiol-induced gene expression when linked to a heterologous promoter. The roles of the ERE- and the AP-1-binding sites in oestrogen receptor-directed transcription from the complete BKV promoter/enhancer (Dunlop...
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