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A truncated T antigen expressed from an alternatively spliced BK virus early mRNA

13 Apr 2009

Abstract excerpt

The early region of BK virus (BKV) is known to encode two well-characterized tumour (T) antigens, large T antigen (TAg) and small T antigen (tAg). In this study, we provide evidence of a third early BKV mRNA that codes for an additional early region product with an apparent molecular mass of 17-20 kDa. This truncated form of TAg (truncTAg) is expressed from an alternatively spliced mRNA that is derived from the...

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PMID: 19264611
DOI: 10.1099/vir.0.009159-0

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