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Article

Regulation of Calreticulin Gene Expression by Calcium

11 Aug 1997

Abstract excerpt

We have isolated and characterized a 12-kb mouse genomic DNA fragment containing the entire calreticulin gene and 2.14 kb of the promoter region. The mouse calreticulin gene consists of nine exons and eight introns, and it spans 4.2 kb of genomic DNA. A 1.8-kb fragment of the calreticulin promoter was subcloned into a reporter gene plasmid containing chloramphenicol acetyltransferase. This construct was then used...

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PMID: 9245785
DOI: 10.1083/jcb.138.3.547

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