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Article

Systematic mutagenesis of the fission yeast Srp54 protein.

Current genetics - 1 Mar 1999

Martínez-Force E, Lakhe-Reddy S, Wise J A

Abstract excerpt

The signal recognition particle (SRP) is a ribonucleoprotein required for targeting a subset of nascent pre-secretory proteins to the endoplasmic reticulum membrane. Of the six SRP polypeptides, the most highly conserved is Srp54p, a modular protein consisting of an amino-terminal (N) domain of unknown function, a central GTPase (G) domain, and a carboxyl-terminal (M) domain implicated in the recognition of both...

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Identifiers

PMID: 10079327
DOI: 10.1007/s002940050437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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