Article
Role of extracellular matrix and Ras in regulation of glomerular epithelial cell proliferation.
The American journal of pathology - 1 Mar 1999
Cybulsky A V, McTavish A J, Papillon J, Takano T
Abstract excerpt
Signals from extracellular matrix (ECM) to growth factor receptors regulate glomerular epithelial cell (GEC) proliferation. Epidermal growth factor (EGF), basic fibroblast growth factor, hepatocyte growth factor (HGF), or thrombin stimulated proliferation of GECs when the cells were adherent to collagen matrices, but not plastic substratum. Furthermore, EGF, HGF, or thrombin activated p42 mitogen-activated...
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