Article
HIV-1 Gag shares a signature motif with annexin (Anx7), which is required for virus replication.
Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 1999
Srivastava M, Cartas M, Rizvi T A, Singh S P, Serio D, Kalyanaraman V S, Pollard H B, Srinivasan A
Abstract excerpt
Genetic and biochemical analyses of the Gag protein of HIV-1 indicate a crucial role for this protein in several functions related to viral replication, including viral assembly. It has been suggested that Gag may fulfill some of the functions by recruiting host cellular protein(s). In our effort to identify structural and functional homologies between Gag and cellular cytoskeletal and secretory proteins involved...
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