Article
Generation and regulation of developing immortalized neural cell lines.
Methods (San Diego, Calif.) - 1 Nov 1998
Gökhan S, Song Q, Mehler M F
Abstract excerpt
The genetic and environmental signals that regulate progressive lineage elaboration in the mammalian brain are poorly understood. In addition, characterization of the developmental profiles of early central nervous system (CNS) stem/ progenitor cells and analysis of the mechanisms involved in their clonal expansion, lineage restriction, and cellular maturation have been fragmentary and elusive. These seminal...
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