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Article

Receptor system response kinetics reveal functional subtypes of native murine and recombinant human GABAA receptors.

The Journal of physiology - 15 Mar 1999

McClellan A M, Twyman R E

Abstract excerpt

1. Regional distinctions in GABA type A (GABAA) miniature IPSC responses are thought to be determined by postsynaptic receptor composition. The kinetics of receptor activation and deactivation were studied using rapid exchange (100 micros) of GABA at excised patches containing recombinant (alpha1beta1gamma2 or alpha2beta1gamma2) and native (cortical) GABAA receptors. 2. Receptors activated by brief (< 1 ms)...

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Identifiers

PMID: 10066899
DOI: 10.1111/j.1469-7793.1999.711ab.x
PMCID: PMC2269184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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