Article
Effect of mutations at the monomer-monomer interface of cAMP receptor protein on specific DNA binding.
The Journal of biological chemistry - 12 Mar 1999
Shi Y, Wang S, Krueger S, Schwarz F P
Abstract excerpt
To determine the thermodynamic role of binding of an operon to cAMP receptor protein (CRP) in the activation of transcription, isothermal titration calorimetry measurements were performed on the binding of three 40-base pair DNA sequences to the cyclic nucleoside complexes of CRP and its mutants...
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