Article
Avian and murine LR8B and human apolipoprotein E receptor 2: differentially spliced products from corresponding genes.
Genomics - 1 Jun 1997
Brandes C, Novak S, Stockinger W, Herz J, Schneider W J, Nimpf J
Abstract excerpt
Apolipoprotein E-mediated lipid metabolism in the central nervous system plays an important role in cholesterol and phospholipid homeostasis of this organ, which is separated from the circulation by the blood-brain barrier. Moreover, in late-onset familial Alzheimer disease the frequency of the apolipoprotein E4 allele is significantly increased and the apoprotein is localized to extracellular plaques, one of the...
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