Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The factor II G20210A and factor V G1691A gene transitions and coronary heart disease.

Thrombosis and haemostasis - 1 Feb 1999

Gardemann A, Arsic T, Katz N, Tillmanns H, Hehrlein F W, Haberbosch W

Abstract excerpt

BACKGROUND: G to A transitions at nucleotide position 20210 of the factor II (Fll) gene and at 1691 of the factor V (FV) gene have been shown to be associated with an increased risk of venous thrombosis. Since it is still unclear whether both gene variations are also related to an increased risk of coronary heart disease (CHD), we studied the relation of both gene variations to coronary artery disease (CAD) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Angiography
Share to Coronary Disease
Share to Diabetes Mellitus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor V

Share to Factor V Deficiency

Share to Hyperlipidemias

Share to Prothrombin

Share to Thrombophilia

Source

Identifiers

PMID: 10063993

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The factor II G20210A and factor V G1691A gene transitions and coronary heart disease.PMID 10063993Read ↗

Increased prevalence of the G20210A prothrombin gene variant in acute coronary syndromes without metabolic or acquired risk factors or with limited extent of disease.Semantic proximity Read ↗

Analysis of polymorphisms Leiden Factor V G1691A and prothrombin G20210A as risk factors for acute myocardial infarction.Semantic proximity Read ↗

Association of FV G1691A Polymorphism but not A4070G With Coronary Artery Disease.Semantic proximity Read ↗

Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.Semantic proximity Read ↗

Genetic polymorphisms and coronary artery disease in the south of France.Semantic proximity Read ↗

Factor V Leiden mutation is not a predisposing factor for acute coronary syndromes.Semantic proximity Read ↗

Coagulation Factors II, V, VII, and X, Prothrombin Gene 20210G→A Transition, and Factor V Leiden in Coronary Artery DiseaseSemantic proximity Read ↗

Combined carrier status of prothrombin 20210A and factor XIII-A Leu34 alleles as a strong risk factor for myocardial infarction: evidence of a gene-gene interaction.Semantic proximity Read ↗

Factor V R506Q mutation-Leiden: an independent risk factor for venous thrombosis but not coronary artery disease.Semantic proximity Read ↗

Interaction of coagulation defects and cardiovascular risk factors: increased risk of myocardial infarction associated with factor V Leiden or prothrombin 20210A.Semantic proximity Read ↗

Factor II activity is similarly increased in patients with elevated apolipoprotein CIII and in carriers of the factor II 20210A allele.Semantic proximity Read ↗

The factor II G20210A gene polymorphism, but not factor V Arg506Gln, is associated with peripheral arterial disease: results of a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.