Article
Functional consequences of nonsynonymous single nucleotide polymorphisms in the CB2 cannabinoid receptor.
Pharmacogenetics and genomics - 1 Mar 2010
Carrasquer Alex, Nebane Nstang M, Williams Walter M, Song Zhao-Hui
Abstract excerpt
OBJECTIVE: To test the hypothesis that the two nonsynonymous single nucleotide polymorphisms at the CB2 cannabinoid receptor gene may have functional consequences on human CB2. METHODS: Q63R, H316Y, and Q63R/H316 mutations were made in recombinant human CB2 by the method of site-directed mutagene...
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