Article
Hepatitis B virus X protein transactivates the inducible nitric oxide synthase promoter.
Hepatology (Baltimore, Md.) - 1 Mar 1999
Amaro M J, Bartolomé J, Carreño V
Abstract excerpt
The capability of hepatitis B virus (HBV) to increase the transcription of the human hepatic inducible nitric oxide synthase (iNOS) by transactivating its promoter has been studied. We have observed by reverse-transcription polymerase chain reaction (RT-PCR) that although the mRNA for the iNOS was almost undetectable in the human hepatoblastoma cell line, HepG2, it was constitutively expressed in the 2.2.15 cell...
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