Article
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.
Journal of the National Cancer Institute - 17 Feb 1999
Ahrendt S A, Chow J T, Xu L H, Yang S C, Eisenberger C F, Esteller M, Herman J G, Wu L, Decker P A, Jen J, Sidransky D
Abstract excerpt
BACKGROUND: Conventional cytologic analysis of sputum is an insensitive test for the diagnosis of non-small-cell lung cancer (NSCLC). We have recently demonstrated that polymerase chain reaction (PCR)-based molecular methods are more sensitive than cytologic analysis in diagnosing bladder cancer. In this study, we examined whether molecular assays could identify cancer cells in bronchoalveolar lavage (BAL) fluid....
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