Article
Bronchoscopic microsampling is a useful complementary diagnostic tool for detecting lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2011
Yasuda Hiroyuki, Soejima Kenzo, Nakayama Sohei, Kawada Ichiro, Nakachi Ichiro, Yoda Satoshi, Satomi Ryosuke, Ikemura Shinnosuke, Terai Hideki, Sato Takashi, Watanabe Hideo, Naoki Katsuhiko, Hayashi Yuichiro, Ishizaka Akitoshi
Abstract excerpt
PURPOSE: Bronchoscopic microsampling (BMS) is a novel and direct method with which to obtain epithelial lining fluid (ELF) from the lungs. Analysis of DNA hypermethylation of tumor suppressor genes (TSGs) is expected to be a sensitive tool for the early detection of lung cancer. It has been reported that the existence of EGFR mutations and EML4-ALK gene rearrangements are related to the sensitivity of...
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