Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Susceptibility to 5‐Aminolevulinic Acid Based Photodynamic Therapy in WHO I Meningioma Cells Corresponds to Ferrochelatase Activity

29 Sept 2010

Abstract excerpt

5-Aminolevulinic acid (5-ALA) is a natural precursor of protoporphyrin IX (PpIX), which can be used as a photosensitizer in photodynamic therapy (PDT). Accumulation of PpIX in benign meningioma cells has been observed previously, its exploitation for PDT, however, was discouraged by inconsistent results. To evaluate PDT for benign meningiomas, we investigated PpIX synthesis in two human meningioma cell lines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nanoplatforms for cancer theranostics
Share to Photodynamic Therapy Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21073472
DOI: 10.1111/j.1751-1097.2010.00821.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Susceptibility to 5‐Aminolevulinic Acid Based Photodynamic Therapy in WHO I Meningioma Cells Corresponds to Ferrochelatase ActivityPMID 21073472Read ↗

The Effects of 5-Aminolevulinic Acid Esters on Protoporphyrin IX Production in Human Adenocarcinoma Cell Lines¶Semantic proximity Read ↗

Mechanism of cell death by 5‐aminolevulinic acid‐based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937Semantic proximity Read ↗

MEK reduces cancer-specific PpIX accumulation through the RSK-ABCB1 and HIF-1α-FECH axesSemantic proximity Read ↗

Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: a comprehensive study on six breast cell lines with varying phenotypes.Semantic proximity Read ↗

Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.Semantic proximity Read ↗

In Vitro Study of Biosynthesis of Protoporphyrin IX Induced By δ-Aminolevulinic Acid in Normal and Cancerous Cells of the Human CervixSemantic proximity Read ↗

Effect of mammalian cell differentiation on response to exogenous 5-aminolevulinic acid.Semantic proximity Read ↗

Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: Dependence on cell density, cell size and cell cycleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.