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Article

Regulation of chamber-specific gene expression in the developing heart by Irx4.

Science (New York, N.Y.) - 19 Feb 1999

Bao Z Z, Bruneau B G, Seidman J G, Seidman C E, Cepko C L

Abstract excerpt

The vertebrate heart consists of two types of chambers, the atria and the ventricles, which differ in their contractile and electrophysiological properties. Little is known of the molecular mechanisms by which these chambers are specified during embryogenesis. Here a chicken iroquois-related homeobox gene, Irx4, was identified that has a ventricle-restricted expression pattern at all stages of heart development....

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Identifiers

PMID: 10024241
DOI: 10.1126/science.283.5405.1161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Regulation of chamber-specific gene expression in the developing heart by Irx4.PMID 10024241Read ↗

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