Article

Investigation into the mechanisms of Stevens-Johnson syndrome and toxic epidermal necrolysis

2019-01-01

Abstract excerpt

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening immune-mediated blistering cutaneous reactions with mortality rates ranging from 10-30%. The pathophysiological mechanisms of SJS/TEN are complex and not fully understood. However, fulminant keratinocyte death and inflammation have been suggested as the major players in the mechanisms of disease. To further understand the mechan...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ffbf1d6e-03bd-54da-bc85-11e924c43c4c
DOI: 10.17638/03056025

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigation into the mechanisms of Stevens-Johnson syndrome and toxic epidermal necrolysisDOI 10.17638/03056025Read

[Recent progress in research of pathogeneses of Stevens-Johnson syndrome and toxic epidermal necrolysis].Semantic proximity Read

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis- An OverviewSemantic proximity Read

Update on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management.Semantic proximity Read

Toxic epidermal necrolysis and Stevens-Johnson syndrome.Semantic proximity Read

Stevens-Johnson syndrome and toxic epidermal necrolysis: clinical patterns, diagnostic considerations, etiology, and therapeutic management.Semantic proximity Read

Stevens-Johnson syndrome and toxic epidermal necrolysis.Semantic proximity Read

A Review of the Pathogenesis of Toxic Epidermal Necrolysis.Semantic proximity Read

High-Mobility Group Box 1 Protein (HMGB1) as a Novel Diagnostic Tool for Toxic Epidermal Necrolysis and Stevens-Johnson SyndromeSemantic proximity Read

Advances in Prognostic Biomarkers and Targeted Immunomodulation in Severe Cutaneous Adverse ReactionsSemantic proximity Read

Current Pharmacogenetic Perspective on Stevens-Johnson Syndrome and Toxic Epidermal NecrolysisSemantic proximity Read

Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.Semantic proximity Read

Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis.Semantic proximity Read