Article
Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.
Clinics in dermatology - 1 Jan 2000
Noe Megan H, Micheletti Robert G
Abstract excerpt
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, immunologically mediated cutaneous adverse reaction characterized by mucous membrane and epidermal detachment, with a mortality ranging from 15% to 25%. Risk factors for the development of SJS/TEN include immune dysregulation, active malignancy, and genetic predisposition. Medications are the most common cause, particularly antimicrobials,...
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