Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Review of the Pathogenesis of Toxic Epidermal Necrolysis.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi - 1 Jan 2016

Kinoshita Yuri, Saeki Hidehisa

Abstract excerpt

Toxic epidermal necrolysis (TEN) is a rare skin condition, most often drug-induced, known for its skin detachment and high mortality. In general, acute TEN is considered a T-cell mediated, type IV hypersensitivity disorder. It mostly results from a cumulative effect of risks from the drug structure, drug metabolism, HLA alleles and T cell clonotypes. However, the precise mechanism of TEN is still unknown....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Annexins
Share to Antigens, Differentiation, T-Lymphocyte
Share to Dermis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Granzymes

Share to Necrosis

Share to Perforin

Share to Stevens-Johnson Syndrome

Source

Identifiers

PMID: 28133001
DOI: 10.1272/jnms.83.216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Review of the Pathogenesis of Toxic Epidermal Necrolysis.PMID 28133001Read ↗

Toxic epidermal necrolysis: current evidence, practical management and future directionsSemantic proximity Read ↗

[Recent progress in research of pathogeneses of Stevens-Johnson syndrome and toxic epidermal necrolysis].Semantic proximity Read ↗

Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.Semantic proximity Read ↗

Toxic epidermal necrolysis: the year in review.Semantic proximity Read ↗

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis- An OverviewSemantic proximity Read ↗

Stevens-Johnson syndrome and toxic epidermal necrolysis: clinical patterns, diagnostic considerations, etiology, and therapeutic management.Semantic proximity Read ↗

Toxic epidermal necrolysis and Stevens-Johnson syndrome.Semantic proximity Read ↗

Recent advances in the genetics and immunology of Stevens-Johnson syndrome and toxic epidermal necrosis.Semantic proximity Read ↗

Stevens-Johnson syndrome and toxic epidermal necrolysis.Semantic proximity Read ↗

Advances in Prognostic Biomarkers and Targeted Immunomodulation in Severe Cutaneous Adverse ReactionsSemantic proximity Read ↗

Current Pharmacogenetic Perspective on Stevens-Johnson Syndrome and Toxic Epidermal NecrolysisSemantic proximity Read ↗

Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.