Article

Genomically Adjusted Radiation Dose Predicts Outcomes in Pediatric Brain Tumors and Supports Biologically Personalized Radiotherapy

2026-08-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Radiotherapy is a cornerstone of treatment for pediatric central nervous system (CNS) tumors, but dose selection remains uniform despite interpatient variability in tumor radiosensitivity. This is consequential in children, for whom toxicity can have lifelong effects. Genomic-adjusted radiation dose (GARD) integrates tumor genomics with delivered radiation dose to quantify t...

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Literature Corpus work: ff637588-dcf4-5560-835a-5c3a32ea95a3
DOI: 10.64898/2026.08.09.26359976

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