Article
Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.
Acta neuropathologica communications - 26 Jul 2018
Gits Hunter C, Anderson Maia, Stallard Stefanie, Pratt Drew, Zon Becky, Howell Christopher, Kumar-Sinha Chandan, Vats Pankaj, Kasaian Katayoon, Polan Daniel, Matuszak Martha, Spratt Daniel E, Leonard Marcia, Qin Tingting, Zhao Lili, Leach James, Chaney Brooklyn, Escorza Nancy Yanez, Hendershot Jacob, Jones Blaise, Fuller Christine, Leary Sarah, Bartels Ute, Bouffet Eric, Yock Torunn I, Robertson Patricia, Mody Rajen, Venneti Sriram, Chinnaiyan Arul M, Fouladi Maryam, Gottardo Nicholas G, Koschmann Carl
Abstract excerpt
With improved survivorship in medulloblastoma, there has been an increasing incidence of late complications. To date, no studies have specifically addressed the risk of radiation-associated diffuse intrinsic pontine glioma (DIPG) in medulloblastoma survivors. Query of the International DIPG Registry identified six cases of DIPG with a history of medulloblastoma treated with radiotherapy. All patients underwent...
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