Article

ER Stress-Mediated Impairment of Hepatic Lipid Export Drives Steatosis in AKI-Induced Remote Liver Injury

2026-05-19

Abstract excerpt

<title>Abstract</title> <p>Background Acute kidney injury (AKI) frequently causes remote organ injury including hepatic steatosis, yet whether lipid accumulation reflects increased synthesis or impaired clearance has not been resolved. Methods We used a murine ischemia-reperfusion AKI model. Unbiased liver proteomics was performed at 24 hours after reperfusion, and dysregulated pathways were identified by Gene...

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Literature Corpus work: ff252a26-1981-515c-b469-e1f2725bc68f
DOI: 10.21203/rs.3.rs-9409706/v1

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ER Stress-Mediated Impairment of Hepatic Lipid Export Drives Steatosis in AKI-Induced Remote Liver InjuryDOI 10.21203/rs.3.rs-9409706/v1Read

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