Article

Tumor-derived KLK8 predicts inferior survival and promotes an immune-suppressive tumor microenvironment in lung squamous cell carcinoma

2023-05-17

Abstract excerpt

Lung squamous cell carcinoma (LUSC) is the second most common lung cancer worldwide, leading to millions of deaths annually. Although immunotherapy has expanded the therapeutic choices for LUSC and achieved considerable efficacy in a subset of patients, many patients could not benefit, and resistance was pervasive. Therefore, it is significant to investigate the mechanisms leading to patients’ poor response to imm...

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Literature Corpus work: febd52d6-8e9e-5d72-8920-dc79677e11f2
DOI: 10.21203/rs.3.rs-2913814/v1

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