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Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia

8 Aug 2018

Abstract excerpt

Preeclampsia is a disease of the mother, fetus and the placenta, and gaps in our understanding of the complex interactions among their disease pathways withheld successful treatment and prevention. The placenta has a key role in the pathogenesis of the terminal pathway characterized by exaggerated maternal systemic inflammation, generalized endothelial damage, hypertension and proteinuria. This sine qua non of...

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Birth, Development, and Health
Pregnancy and preeclampsia studies
Reproductive System and Pregnancy

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30135684
DOI: 10.3389/fimmu.2018.01661

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