Article

Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Material From Neighboring Cells Using Intracellular Monitoring—a Novel Mechanism of Antigen Acquisition

2023-07-25

Abstract excerpt

<h4>ABSTRACT</h4> Macrophages and dendritic cells (DCs) in peripheral tissue interact closely with their local microenvironment by scavenging protein and nucleic acids released by neighboring cells. Material transfer between cell types is necessary for pathogen detection and antigen presentation, but thought to be relatively limited in scale. Recent reports, however, demonstrate that the quantity of transferred m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fe8d18f2-861c-52be-a796-1f1eb5c43022
DOI: 10.1101/2023.07.22.550169

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Material From Neighboring Cells Using Intracellular Monitoring—a Novel Mechanism of Antigen AcquisitionDOI 10.1101/2023.07.22.550169Read

Langerhans Cells: Sensing the Environment in Health and Disease.Semantic proximity Read

Dermis resident macrophages orchestrate localized ILC2-eosinophil circuitries to maintain their M2-like properties and promote non-healing cutaneous leishmaniasisSemantic proximity Read

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.Semantic proximity Read

Mast cells acquire MHCII from dendritic cells during skin inflammation.Semantic proximity Read

Genetic tagging shows increased frequency and longevity of antigen-presenting, skin-derived dendritic cells in vivo.Semantic proximity Read

Ontogeny and function of murine epidermal Langerhans cells.Semantic proximity Read

Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic developmentSemantic proximity Read

Identification of a novel population of Langerin+ dendritic cells.Semantic proximity Read

Uncovering the Mysteries of Langerhans Cells, Inflammatory Dendritic Epidermal Cells, and Monocyte-Derived Langerhans Cell-Like Cells in the Epidermis.Semantic proximity Read

Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells.Semantic proximity Read

STOP floxing around: Specificity and leakiness of inducible Cre/loxP systems.Semantic proximity Read

Langerin-expressing dendritic cells in gut-associated lymphoid tissues.Semantic proximity Read