Article
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.
Nature - 29 Aug 2002
Boes Marianne, Cerny Jan, Massol Ramiro, Op den Brouw Marjolein, Kirchhausen Tom, Chen Jianzhu, Ploegh Hidde L
Abstract excerpt
Assembly of major histocompatibility complex (MHC) molecules, which present antigen in the form of short peptides to T lymphocytes, occurs in the endoplasmic reticulum; once assembled, these molecules travel from the endoplasmic reticulum to their final destination. MHC class II molecules follow...
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