Article

Global Epigenetic Analysis Reveals H3K27 Methylation as a Mediator of Double Strand Break Repair

2021-09-20

Abstract excerpt

The majority of cancer patients is treated with ionizing radiation (IR), a relatively safe and effective treatment considered to target tumors by inducing DNA double strand breaks (DSBs). Despite clinical interest in increasing the efficacy of IR by preventing successful DSB repair, few effective radio-adjuvant therapies exist. Extensive literature suggests that chromatin modifiers play a role in the DSB repair an...

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Literature Corpus work: fe51ee1c-63ab-5fc5-9633-f8fd07058465
DOI: 10.1101/2021.09.20.461136

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