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Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy

24 Mar 2014

Abstract excerpt

Radiotherapy (RT) is a central treatment modality for breast cancer patients. The purpose of our study was to investigate the DNA methylation changes in tumors following RT, and to identify epigenetic markers predicting treatment outcome. Paired biopsies from patients with inoperable breast cancer were collected both before irradiation (n = 20) and after receiving 10-24 Gray (Gy) (n = 19). DNA methylation...

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PMID: 24658971
DOI: 10.1002/ijc.28862

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