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Dose Escalation Biodistribution, Positron Emission Tomography/Computed Tomography Imaging and Dosimetry of a Highly Specific Radionuclide-labeled Non-blocking Nanobody

2021-05-17

Abstract excerpt

<title>Abstract</title> <p><bold>Backgroud:</bold> Immunotherapy is a valuable option for the treatment of cancers, and the curative effect anti-PD-1/PD-L1 therapy correlates closely with PD-L1 expression levels. Positron emission tomography (PET) imaging of PD-L1 expression is feasible using <sup>68</sup>Ga-NOTA-Nb109 nanobodies. <sup>68</sup>Ga-NOTA-Nb109 was generated by radionuclide (<sup>68</sup>Ga) labeling...

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Literature Corpus work
fe18da50-ee7c-575e-a339-2d67c93578ea
DOI
10.21203/rs.3.rs-499313/v1
Open publication

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